Find Medical Office Space for Rent in San Antonio, TX

Secure Healthcare Office Space in San Antonio Today

Your San Antonio practice location should capture more patients. We identify commercial spaces with proven patient demand patterns and negotiates lease terms that reduce occupancy costs while securing expansion rights. Browse San Antonio medical office spaces that will support profitable growth.

Verified Medical Office Listings

Medical Practice Spaces Now Leasing in San Antonio, TX

See what’s available in San Antonio’s medical real estate market – 32+ lease opportunities for dental practices, specialty clinics, and healthcare facilities.

Title	Location	Address	Sale or Lease	Listing Status	hf:tax:location	hf:tax:sale_or_lease	hf:tax:listing_status
Maine Medical Real Estate For Sale/Lease	Maine	Maine, ME	Sale or Lease	Spaces Available	maine	sale-or-lease	spaces-available
Medical Office For Sale in Plano TX \| 938 SF Turnkey Medical Facility	Dallas Fort Worth	3465 National Drive, Plano, TX 75025	Sale	Spaces Available	dallas-fort-worth texas	sale	spaces-available
Medical Office For Lease in Prosper TX \| 2,894 SF Modern Space	Dallas Fort Worth, Prosper	123 Whispering Gables Drive, Suite 20 Prosper, TX 75078	Lease	Spaces Available	dallas-fort-worth prosper texas	lease	spaces-available
Medical Office Space Leander TX – Pointe 183 Development	Austin, Leander	10861 183A Leander, TX 78641	Lease	Spaces Available	austin leander texas	lease	spaces-available
Retail Space for Lease Plano TX \| Prime 18,500 SF Development Opportunity	Dallas Fort Worth, Plano	4065 E Plano Pkwy, Plano, TX 75074	Lease	Spaces Available	dallas-fort-worth plano texas	lease	spaces-available
Medical Office for Lease Hurst TX \| 2,100 SF Turnkey Facility	Dallas Fort Worth, Hurst	804 NE Mall Blvd, Hurst, TX 76053	Lease	Spaces Available	dallas-fort-worth hurst texas	lease	spaces-available
Dental Office for Lease Houston TX \| First-Generation Suite	Houston, Texas	10101 Bissonnet Street, Houston, TX 77036	Lease	Spaces Available	houston texas	lease	spaces-available
Medical Office Space Sienna TX \| New 16,000 SF by MD Anderson	Houston, Sienna	State Hwy 6 and Sienna Ranch Rd, Missouri City, TX	Lease	Spaces Available	houston sienna texas	lease	spaces-available
Medical Office for Lease Austin TX \| Prime 2,377 SF South Location	Austin, Texas	6211 W William Cannon Drive, Austin, TX 78749	Lease	Spaces Available	austin texas	lease	spaces-available
Medical Office for Sale Coppell TX \| 2,281 SF Move-In Ready Condo	Coppell, Dallas Fort Worth	149 TX, 121 Suite 105, Coppell, TX 75019	Sale	Spaces Available	coppell dallas-fort-worth texas	sale	spaces-available
Medical Office For Lease Fort Worth TX \| Prime 7th Street Location	Dallas Fort Worth	2831 W 7th Street, Fort Worth, TX 76107	Lease	Spaces Available	dallas-fort-worth texas	lease	spaces-available
Second Generation Dental Space in Cleburne, TX	Cleburne, Dallas Fort Worth	Cleburne, TX	Sale or Lease	Spaces Available	cleburne dallas-fort-worth texas	sale-or-lease	spaces-available
Commercial Land For Sale in Cleburne TX \| Prime 2.81 AC Development Opportunity	Cleburne, Dallas Fort Worth	1808 West Henderson Street, Cleburne, TX 76033	Sale	Vacant site	cleburne dallas-fort-worth texas	sale	vacant-site
Medical Office South Austin \| Prime 4,469 SF Investment Opportunity	Austin, Texas	12117 Menchaca Road, Austin, TX 78748	Sale	Spaces Available	austin texas	sale	spaces-available
Medical Office For Sublease Westlake \| Turnkey 1,987 SF Space	Austin, Texas	Medical-Office-For-Sublease-Westlake-1987SF-Turnkey-Space-Davenport-Village.pdf	Lease	Spaces Available	austin texas	lease	spaces-available
Medical Office for Lease in Southlake TX \| Modern 2,635 SF Healthcare Space	Dallas Fort Worth, Southlake	2915 E Southlake Blvd, Southlake, TX 76092	Lease	Spaces Available	dallas-fort-worth southlake texas	lease	spaces-available
Class A South Austin Medical Office \| New Construction Suites with Surgery Center	Austin, Texas	9010 Brodie Lane, Austin, TX 78748	Lease	Spaces Available	austin texas	lease	spaces-available
Medical Space For Sale or Lease in Georgetown TX \| 5,465 SF New Construction	Austin, Georgetown	2021 Kaufman Loop, Unit 110, Georgetown, TX 78628	Sale or Lease	Spaces Available	austin georgetown-austin texas	sale-or-lease	spaces-available
Retail Space For Sale in South Austin TX \| Versatile 1,256 SF Storefront	Austin, Texas	4361 S Congress Ave Suite 106 Austin, TX 78745	Sale	Spaces Available	austin texas	sale	spaces-available
Dental Office For Sale in San Antonio TX \| Established Somerset Practice	San Antonio, Texas	1445 Somerset Road # 4, San Antonio, TX 78211	Sale	Spaces Available	san-antonio texas	sale	spaces-available
Retail Space For Lease in East Austin TX \| Prime 4,599 SF Near Mueller	Austin, Texas	4100 E 51st Street, Austin, TX 78723	Lease	Spaces Available	austin texas	lease	spaces-available
Medical Condo For Sale or Lease in Austin TX \| Professional 4,889 SF Suite	Austin, Texas	3807 Spicewood Springs Road, Austin, TX 78759	Sale or Lease	Spaces Available	austin texas	sale-or-lease	spaces-available
Medical Office For Sale or Lease in Round Rock TX \| Prime 2,118 SF Condo	Austin, Round Rock	4010 Sandy Brook Drive, Round Rock, TX 78665	Sale or Lease	Spaces Available	austin round-rock texas	sale-or-lease	spaces-available
Medical Office For Lease in Dripping Springs TX \| Sawyer Ranch Medical Towers	Austin, Dripping Springs	13830 Sawyer Ranch Road, Dripping Springs, TX 78620	Lease	Spaces Available	austin dripping-springs texas	lease	spaces-available
Medical Office Space For Lease in North Austin \| Turnkey 1,905 SF Medical Condo	Austin, Texas	12319 N Mopac Expy, Austin, TX 78758	Lease	Spaces Available	austin texas	lease	spaces-available
Medical Condo For Lease in Cedar Park \| 1,892 SF Class A Office Space	Austin, Cedar Park	1513 E New Hope Drive, Bldg B, Austin, TX 78641	Lease	Fully Leased	austin cedar-park texas	lease	fully-leased
Commercial Land For Sale in Garland TX \| Prime 1.258 AC Development Opportunity	Dallas Fort Worth, Garland, Texas	SEQ I-635 & Centerville Road, Garland, Texas 75041	Sale	Vacant site	dallas-fort-worth garland texas	sale	vacant-site
New Construction For Lease in Bee Cave TX \| Professional Building on Highway 71	Austin, Texas	State Highway 71 & Del Dios Way, Austin, TX 78738	Lease	Spaces Available	austin texas	lease	spaces-available
Office Building For Sale in Humble TX \| Prime 21,705 SF Investment Opportunity	Houston, Texas	19411 McKay Boulevard, Humble, TX 77338	Sale	Spaces Available	houston texas	sale	spaces-available
Dental Office For Lease in Humble TX \| Second Generation Space with 4 Operatories	Houston, Humble	19411 McKay Drive Humble, TX 77338	Lease	Spaces Available	houston humble texas	lease	spaces-available
Office Space For Lease in Boerne TX \| Prime Location with Excellent Accessibility	Boerne, San Antonio, Texas	415 South School Street, Boerne, TX 78006	Lease	Spaces Available	boerne san-antonio texas	lease	spaces-available
Medical Office For Sale in Aransas Pass TX \| 60,445 SF Healthcare Anchor Opportunity	Aransas Pass, Texas	1711 W Wheeler Ave, Aransas Pass TX, 78336	Sale or Lease	Spaces Available	aransas-pass texas corpus	sale-or-lease	spaces-available
Medical Office For Sale or Lease in Georgetown TX \| 17,000 SF Class A DB Woods Development	Austin, Georgetown	NEQ Highway 29 & DB Woods	Sale or Lease	Spaces Available	austin georgetown-austin texas	sale-or-lease	spaces-available
Medical Office For Lease in Hutto TX \| 2,000 SF Professional Space at 401 Exchange Blvd	Austin, Hutto	401 Exchange Blvd, Hutto, TX 78634	Lease	Spaces Available	austin hutto texas	lease	spaces-available

Healthcare Expertise General Commercial Real Estate Brokers Can't Match

Your Practice Speaks Medicine. Your Broker Should Too.

Find available medical office space in San Antonio, TX.

San Antonio Medical Real Estate Experts

We catch lease traps that hurt practices. We know which clauses kill future sale value, which locations fail for your specialty, and which contractors actually finish medical buildouts on time. General commercial real estate brokers miss these details. Your practice profitability depends on getting them right.

San Antonio Medical Real Estate Expertise That Drives New Patients

Take Alamo Heights, where families with children grew 47%. Then you have the Northwest Side adding 6,800 high-income households looking for concierge care. Our San Antonio market data helps you pick locations where medical practices make money.

San Antonio Specialty Site Selection Expertise

Details matter. Cardiology spaces in Stone Oak need 3,500 square feet for stress testing equipment. Pediatric offices near the Medical Center require 2,800 square feet with specialized ventilation. Our site selection ensures your San Antonio lease covers medical gas infrastructure, ADA compliance, and diagnostic equipment needs.

Work With Commercial Real Estate Brokers to Find the Right Space

We protect your data. See our privacy policy for details.

San Antonio Medical Real Estate Perfected. Every Service. Every Specialty. Every Time.

Our San Antonio medical office space brokers help doctors, dentists, and healthcare providers find locations built for practice success.

5-star Google Rated commercial real estate brokerage in San Antonio, TX.

Start Your San Antonio Healthcare Property Search Here

You focus on patient care while we locate an ideal San Antonio medical space and negotiate favorable lease terms. Our healthcare-focused approach saves you time and money while securing locations that support long-term practice success.

Our healthcare real estate agents in San Antonio, TX are experts in helping clients find the best possible office space.

Find the Right San Antonio Medical Market

We map out where your competitors are in San Antonio so you can see which neighborhoods are oversaturated and which ones need your specialty. We keep tracking your location performance and ensure zoning compliance to avoid violations. Get a comprehensive market study to make the right choice.

Fill Your San Antonio Medical Space

Don’t waste time with generic tenants who break leases early. We connect your property directly to our network of San Antonio physicians and specialists needing long-term office space. Our healthcare leasing team structures multi-year agreements averaging 7+ years while managing all tenant communications and renewals. You get consistent rental income while we handle relationships. Connect with our medical leasing specialists today.

Why Healthcare Practices Need Specialized Real Estate Brokers

Practice Real Estate Group vs other broker types
	Practice Real Estate Group	General Commercial Brokers	National CRE Firms
Market Expertise	✅ 100% healthcare focus with specialty specific demographic analysis.	Treats medical like any standard office space.	Corporate red tape with minimal healthcare specialization.
Medical Space Knowledge	✅ Expert in medical office build outs ADA medical gas and HVAC requirements.	Basic knowledge with gaps in practice needs.	Refers to outside specialists, adding time and money.
Patient Demographics	✅ Healthcare specific data insurance coverage and competition mapping.	Generic data without patient utilization insight.	Standard reports.
Lease Negotiations	✅ Medical focused lease terms expansion rights and equipment clauses.	Standard terms missing key healthcare protections.	Corporate terms with less focus on individual practices.
Professional Network	✅ Vetted healthcare network contractors, lenders, and vendors.	General contractors, limited healthcare ties.	Corporate vendors that exceed practice budgets.
Practice Understanding	✅ Deep specialty knowledge workflow and patient accessibility needs.	One size fits all approach, limited expertise.	Focus on square footage vs practice function.
Client Focus	✅ Dedicated attention from expert five star medical real estate agents.	Attention split across property types.	Priority on the largest corporate deals.

Dental Practices

Rent a Dental Office in San Antonio

Choosing the right San Antonio location gets you to profitability 6-12 months faster. Stone Oak’s $95,000 median household income means higher treatment acceptance rates, while Medical Center areas provide steady insurance patient flow. Northside neighborhoods project 20% growth through 2027, bringing thousands of new patients. Let’s secure your ideal dental location now.

Medical Practices

Find the Right San Antonio Medical Office Building

Expanding diagnostic capabilities requires medical office space for rent with proper electrical loads and imaging-ready rooms. San Antonio’s Methodist and Baptist systems within five miles of your practice ensures smooth referrals and EHR connectivity for coordinated care. Spaces near Stone Oak’s 45,000 seniors or Medical Center’s diverse populations help you reach 25+ daily visits by month six. Connect with our medical real estate specialists now to find the perfect spot.

Internal medicine practices
Pediatric doctor offices
Family medicine clinics
Cardiology practices
Dermatology clinics
Orthopedic clinics
Optometry offices

Diagnostic imaging centers
Mental health practices
Physical therapy clinics
Senior living spaces
Chiropractic offices
Urgent care centers
Veterinary clinics
Wellness spaces

Speciality Practices

San Antonio Specialty Medical Office Space Solutions

Specialty locations connect you with San Antonio’s referral networks where physicians already send patients. We handle zoning compliance and ensure imaging centers get proper shielding and power requirements, preventing costly delays. Corporate districts need mental health and stress-related services. Building your wellness reputation here captures growing demand. Turn location into your competitive advantage.

San Antonio Provides Ideal Conditions for Medical Practice Growth

San Antonio’s 1.53 million residents grow 1.23% annually with $62,917 median household income, which leads to solid practice revenue potential. VIA runs 8 medical center routes, including Primo 100 BRT connecting patients every 15 minutes. South and East sides’ 64% Hispanic population remains underserved. University Health’s $1.5 billion expansion adds three hospitals by 2027 targeting these demographics. Book your comprehensive market assessment today.

Single Site Study

$399/site

Know exactly where ideal patients are. Our single-site analysis maps demographics, income, and market saturation rates, revealing underserved pockets where demand exceeds supply. Determine if your desired location generates the patient volume and revenue you need. Order your market intelligence report now.

Custom Area Study

$300/100K people

Discover highest-opportunity locations across any market. Our custom study divides regions into 3-mile catchment zones, scoring each for practice viability. Perfect for multi-site expansion or location selection. Compare dozens of potential sites simultaneously. Strategic intelligence priced per 100,000 population.

Get a Rental Expense Estimate

Estimate your yearly rent, startup loan amount, buildout costs, and more.

Real Estate Expense Estimator

Practice Real Estate Expense and Timeline Estimate Generator

With 4 quick questions and about one minute of your time, we can send you an estimate of what your monthly rent, property expenses, and build-out loan payment for your practice will be.

We also include a purchasing budget equivalent to those rental rates if you are considering purchasing your real estate. Finally, you'll get a general timeline on when you might expect to be open.

Your packet will be emailed to you instantly when you hit submit.

Our Proven Commercial Office Leasing Process

Step 1

Practice Needs Analysis

Step 2

Research/ Site Selection

Step 3

Property Tours & Evaluation

Step 4

Lease Negotiation & Terms

Step 5

Opening Coordination

San Antonio Medical Real Estate Questions & Answers

Where in San Antonio is right for my practice location?

Your best practice location in San Antonio depends on matching your specialty to demographic patterns and growth trends. Stone Oak works well for pediatric practices due to young families, while the Medical Center area suits specialists needing hospital referrals, and Alamo Heights attracts cosmetic practices targeting affluent patients.

Look at healthcare utilization rates in each area, evaluate how your services connect with nearby labs and imaging centers, and consider expansion potential as neighborhoods develop. The right location balances current patient demand with future growth opportunities.

How much should I budget per square foot in San Antonio?

San Antonio medical office space typically runs $24 to $36 per square foot annually. Ground floor spaces command premium rates of $30 to $36, while upper floors offer savings at $24 to $30. Advertised base rent don’t tell the whole story. NNN leases add taxes, insurance, and CAM fees, though full-service options simplify budgeting.

Monthly examples help you plan: data-driven location validation spaces (1,000 sf) run $2,000 to $2,500, dermatology practices (1,500 to 2,000 sf) need $3,750 to $6,000, and small groups (2,500 to 3,000 sf) budget $5,000 to $7,500. Security and access control adds $3.50 to $15 per door. Talk to our commercial real estate agents for current pricing.

Can agents improve deals on medical spaces I've already located?

Yes, we can often improve deals on spaces you’ve found by 15-30% through professional negotiation tactics most practitioners don’t know. We protect your practice against hidden liabilities, secure expansion rights for future growth, and negotiate renewal option rate caps that prevent surprise rent increases.

Plus, we handle lease protection elements like compliance verification for medical use, insurance requirement adjustments, and HIPAA space configuration needs that could cost thousands if missed. No cost to you, significant savings guaranteed since we’re paid by landlords while representing your interests.