Find a Medical Office Space for Lease in Plano, TX

Find Healthcare Office Spaces Available Now in Plano, TX

Stop paying too much for healthcare office space in Plano. We connect you with properties that fit your budget and patient needs through exclusive market data and direct owner relationships. Browse healthcare office spaces in Plano now.

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Search Plano Medical Office Space For Rent Below

Get more space for less money with medical offices from 1,200-8,500 sqft in Plano’s growing healthcare corridor. These properties deliver the patient accessibility and parking your practice needs to grow revenue.
TitleLocationAddressSale or LeaseListing Statushf:tax:locationhf:tax:sale_or_leasehf:tax:listing_status
Maine Medical Real Estate For Sale/Lease
Maine Medical Real Estate For Sale/LeaseMaineMaine, MESale or LeaseSpaces Availablemainesale-or-leasespaces-available
Medical office Plano TX clinical treatment room with specialized medical chair and professional healthcare equipment
Medical Office For Sale in Plano TX | 938 SF Turnkey Medical FacilityDallas Fort Worth3465 National Drive, Plano, TX 75025SaleSpaces Availabledallas-fort-worth texassalespaces-available
Medical office Prosper TX at Whispering Gables Office Park featuring modern 2020 construction
Medical Office For Lease in Prosper TX | 2,894 SF Modern SpaceDallas Fort Worth, Prosper123 Whispering Gables Drive, Suite 20 Prosper, TX 75078LeaseSpaces Availabledallas-fort-worth prosper texasleasespaces-available
Medical Office Space Leander TX - Pointe 183 Development
Medical Office Space Leander TX – Pointe 183 DevelopmentAustin, Leander10861 183A Leander, TX 78641LeaseSpaces Availableaustin leander texasleasespaces-available
Retail space for lease Plano TX at Plano Business Park showing modern commercial building exterior with glass windows and professional landscaping
Retail Space for Lease Plano TX | Prime 18,500 SF Development OpportunityDallas Fort Worth, Plano4065 E Plano Pkwy, Plano, TX 75074LeaseSpaces Availabledallas-fort-worth plano texasleasespaces-available
Medical space for sublease Hurst TX exterior view at The Shops at North East Mall showing signage and retail medical location
Medical Office for Lease Hurst TX | 2,100 SF Turnkey FacilityDallas Fort Worth, Hurst804 NE Mall Blvd, Hurst, TX 76053LeaseSpaces Availabledallas-fort-worth hurst texasleasespaces-available
Dental Office for Lease Houston TX | First-Generation Suite
Dental Office for Lease Houston TX | First-Generation SuiteHouston, Texas10101 Bissonnet Street, Houston, TX 77036LeaseSpaces Availablehouston texasleasespaces-available
Medical Office Space Sienna TX | New 16,000 SF by MD Anderson
Medical Office Space Sienna TX | New 16,000 SF by MD AndersonHouston, SiennaState Hwy 6 and Sienna Ranch Rd, Missouri City, TXLeaseSpaces Availablehouston sienna texasleasespaces-available
Medical office for lease Austin TX featuring 2,377 SF second-generation space in South Austin
Medical Office for Lease Austin TX | Prime 2,377 SF South LocationAustin, Texas6211 W William Cannon Drive, Austin, TX 78749LeaseSpaces Availableaustin texasleasespaces-available
Medical Office for Sale Coppell TX | 2,281 SF Move-In Ready Condo
Medical Office for Sale Coppell TX | 2,281 SF Move-In Ready CondoCoppell, Dallas Fort Worth149 TX, 121 Suite 105, Coppell, TX 75019SaleSpaces Availablecoppell dallas-fort-worth texassalespaces-available
Medical office Fort Worth featuring 1,569 SF turn-key space on 7th Street
Medical Office For Lease Fort Worth TX | Prime 7th Street LocationDallas Fort Worth2831 W 7th Street, Fort Worth, TX 76107LeaseSpaces Availabledallas-fort-worth texasleasespaces-available
Second Generation Dental Space in Cleburne, TX
Second Generation Dental Space in Cleburne, TXCleburne, Dallas Fort WorthCleburne, TXSale or LeaseSpaces Availablecleburne dallas-fort-worth texassale-or-leasespaces-available
Commercial Land For Sale in Cleburne TX | Prime 2.81 AC Development Opportunity
Commercial Land For Sale in Cleburne TX | Prime 2.81 AC Development OpportunityCleburne, Dallas Fort Worth1808 West Henderson Street, Cleburne, TX 76033SaleVacant sitecleburne dallas-fort-worth texassalevacant-site
Medical office South Austin at intersection of Menchaca Rd and FM 1626 with high visibility
Medical Office South Austin | Prime 4,469 SF Investment OpportunityAustin, Texas12117 Menchaca Road, Austin, TX 78748SaleSpaces Availableaustin texassalespaces-available
Medical Office For Sublease Westlake | Turnkey 1,987 SF Space
Medical Office For Sublease Westlake | Turnkey 1,987 SF SpaceAustin, TexasMedical-Office-For-Sublease-Westlake-1987SF-Turnkey-Space-Davenport-Village.pdfLeaseSpaces Availableaustin texasleasespaces-available
Medical Office for Lease in Southlake TX | Modern 2,635 SF Healthcare Space
Medical Office for Lease in Southlake TX | Modern 2,635 SF Healthcare SpaceDallas Fort Worth, Southlake2915 E Southlake Blvd, Southlake, TX 76092LeaseSpaces Availabledallas-fort-worth southlake texasleasespaces-available
Class A South Austin Medical Office | New Construction Suites with Surgery Center
Class A South Austin Medical Office | New Construction Suites with Surgery CenterAustin, Texas9010 Brodie Lane, Austin, TX 78748LeaseSpaces Availableaustin texasleasespaces-available
Medical Space For Sale or Lease in Georgetown TX | 5,465 SF New Construction
Medical Space For Sale or Lease in Georgetown TX | 5,465 SF New ConstructionAustin, Georgetown2021 Kaufman Loop, Unit 110, Georgetown, TX 78628Sale or LeaseSpaces Availableaustin georgetown-austin texassale-or-leasespaces-available
Retail Space For Sale in South Austin TX | Versatile 1,256 SF Storefront
Retail Space For Sale in South Austin TX | Versatile 1,256 SF StorefrontAustin, Texas4361 S Congress Ave Suite 106 Austin, TX 78745SaleSpaces Availableaustin texassalespaces-available
Dental Office For Sale in San Antonio TX | Established Somerset Practice
Dental Office For Sale in San Antonio TX | Established Somerset PracticeSan Antonio, Texas1445 Somerset Road # 4, San Antonio, TX 78211SaleSpaces Availablesan-antonio texassalespaces-available
Retail Space For Lease in East Austin TX | Prime 4,599 SF Near Mueller
Retail Space For Lease in East Austin TX | Prime 4,599 SF Near MuellerAustin, Texas4100 E 51st Street, Austin, TX 78723LeaseSpaces Availableaustin texasleasespaces-available
Medical Condo For Sale or Lease in Austin TX | Professional 4,889 SF Suite
Medical Condo For Sale or Lease in Austin TX | Professional 4,889 SF SuiteAustin, Texas3807 Spicewood Springs Road, Austin, TX 78759Sale or LeaseSpaces Availableaustin texassale-or-leasespaces-available
Medical Office For Sale or Lease in Round Rock TX | Prime 2,118 SF Condo
Medical Office For Sale or Lease in Round Rock TX | Prime 2,118 SF CondoAustin, Round Rock4010 Sandy Brook Drive, Round Rock, TX 78665Sale or LeaseSpaces Availableaustin round-rock texassale-or-leasespaces-available
Medical office Dripping Springs TX featuring modern Sawyer Ranch Medical Towers building with stone facade and professional landscaping
Medical Office For Lease in Dripping Springs TX | Sawyer Ranch Medical TowersAustin, Dripping Springs13830 Sawyer Ranch Road, Dripping Springs, TX 78620LeaseSpaces Availableaustin dripping-springs texasleasespaces-available
Medical office North Austin exterior view of Plaza North medical building with professional landscaping and modern architecture near St. David's Medical Center.
Medical Office Space For Lease in North Austin | Turnkey 1,905 SF Medical CondoAustin, Texas12319 N Mopac Expy, Austin, TX 78758LeaseSpaces Availableaustin texasleasespaces-available
Medical Condo For Lease in Cedar Park | 1,892 SF Class A Office Space
Medical Condo For Lease in Cedar Park | 1,892 SF Class A Office SpaceAustin, Cedar Park1513 E New Hope Drive, Bldg B, Austin, TX 78641LeaseFully Leasedaustin cedar-park texasleasefully-leased
Commercial land Garland TX aerial view showing 1.258 AC site adjacent to Winco Foods near I-635
Commercial Land For Sale in Garland TX | Prime 1.258 AC Development OpportunityDallas Fort Worth, Garland, TexasSEQ I-635 & Centerville Road, Garland, Texas 75041SaleVacant sitedallas-fort-worth garland texassalevacant-site
New Construction For Lease in Bee Cave TX | Professional Building on Highway 71
New Construction For Lease in Bee Cave TX | Professional Building on Highway 71Austin, TexasState Highway 71 & Del Dios Way, Austin, TX 78738LeaseSpaces Availableaustin texasleasespaces-available
Building
Office Building For Sale in Humble TX | Prime 21,705 SF Investment OpportunityHouston, Texas19411 McKay Boulevard, Humble, TX 77338SaleSpaces Availablehouston texassalespaces-available
Exceptional second-generation dental office available for lease.
Dental Office For Lease in Humble TX | Second Generation Space with 4 OperatoriesHouston, Humble19411 McKay Drive Humble, TX 77338LeaseSpaces Availablehouston humble texasleasespaces-available
Office Space For Lease in Boerne TX | Prime Location with Excellent Accessibility
Office Space For Lease in Boerne TX | Prime Location with Excellent AccessibilityBoerne, San Antonio, Texas415 South School Street, Boerne, TX 78006LeaseSpaces Availableboerne san-antonio texasleasespaces-available
Aransas Pass Healthcare Space
Medical Office For Sale in Aransas Pass TX | 60,445 SF Healthcare Anchor OpportunityAransas Pass, Texas1711 W Wheeler Ave, Aransas Pass TX, 78336Sale or LeaseSpaces Availablearansas-pass texas corpussale-or-leasespaces-available
Medical Office For Sale or Lease in Georgetown TX | 17,000 SF Class A DB Woods Development
Medical Office For Sale or Lease in Georgetown TX | 17,000 SF Class A DB Woods DevelopmentAustin, GeorgetownNEQ Highway 29 & DB WoodsSale or LeaseSpaces Availableaustin georgetown-austin texassale-or-leasespaces-available
Located in the growing Hutto Community right down the street from the fire station.  This is a great location for a medical office due to an optometrist and dentist being located at the project.  General office use is also allowed and it is near multiple eateries and retail shops.
Medical Office For Lease in Hutto TX | 2,000 SF Professional Space at 401 Exchange BlvdAustin, Hutto401 Exchange Blvd, Hutto, TX 78634LeaseSpaces Availableaustin hutto texasleasespaces-available
Healthcare Expertise General Commercial Real Estate Brokers Can't Match

Plano Medical Office Real Estate Brokers Specializing in Healthcare Properties

Find available medical office space in Plano, TX.

Plano Healthcare Property Professionals

Other brokers treat your medical practice like any office tenant. We know which lease terms protect your practice value. Our healthcare commercial real estate experience means you get advisors who understand medical office space lease requirements from day one.

Plano Medical Market Intelligence

West Plano shows 52% population growth among households earning over $200K while Legacy West added 4,600 affluent professionals needing concierge care. Our Plano research ensures you choose locations where patient demand already exists.

Healthcare Site Selection Services for Plano

Your medical practice deserves a location selected specifically for your specialty's needs. We review properties throughout Plano from Willow Bend to The Colony border, matching spaces from 1,800 sqft urgent care centers to 5,500 sqft specialty clinics with your operational requirements. Our property evaluation examines lease terms, infrastructure capacity, and compliance factors that impact your practice success and patient satisfaction in your chosen neighborhood.

Work With Commercial Real Estate Brokers to Find the Right Space

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Plano Medical Real Estate Expertise You Can Count On

Healthcare professionals in Plano need practice space that accommodates modern equipment while balancing startup costs with growth potential. We work with doctors, dentists, and specialists through site selection and lease negotiations.
5-star Google Rated commercial real estate brokerage in Plano, TX.

Maximize Your Plano Medical Office Space Investment

We increase Plano medical real estate practicec value through healthcare market analysis and expert lease negotiations. Our process saves significant money vs generic brokers while securing locations and terms that support practice growth and future sale opportunities.
Our healthcare real estate agents in Plano, TX are experts in helping clients find the best possible office space.

Professional Healthcare Market Planning in Plano

Lease negotiations improve when supported by data showing patient flow patterns and accessibility factors in Plano locations. We evaluate traffic and demographics to avoid costly relocation and business disruption. Order comprehensive market study for informed decisions.

List With Us, Get Great Healthcare Tenants Fast

Eliminate time-consuming marketing and screening tasks. We use healthcare-specific vetting protocols with professional photography and virtual tours that attract serious medical practices. Our network provides access to premium tenants seeking long-term Plano offices. You get qualified leads while we handle requirements generic brokers miss. Maximize your property’s medical leasing potential.

Why Healthcare Professionals Choose Specialized Commercial Real Estate Brokerage

Practice Real Estate Group vs other broker types
Practice Real Estate Group is the best healthcare real estate firm. Practice Real Estate Group General Commercial Brokers National CRE Firms
Market Expertise 100% healthcare focus with specialty specific demographic analysis. Treats medical like any standard office space. Corporate red tape with minimal healthcare specialization.
Medical Space Knowledge Expert in medical office build outs ADA medical gas and HVAC requirements. Basic knowledge with gaps in practice needs. Refers to outside specialists, adding time and money.
Patient Demographics Healthcare specific data insurance coverage and competition mapping. Generic data without patient utilization insight. Standard reports.
Lease Negotiations Medical focused lease terms expansion rights and equipment clauses. Standard terms missing key healthcare protections. Corporate terms with less focus on individual practices.
Professional Network Vetted healthcare network contractors, lenders, and vendors. General contractors, limited healthcare ties. Corporate vendors that exceed practice budgets.
Practice Understanding Deep specialty knowledge workflow and patient accessibility needs. One size fits all approach, limited expertise. Focus on square footage vs practice function.
Client Focus Dedicated attention from expert five star medical real estate agents. Attention split across property types. Priority on the largest corporate deals.

Dental Practices

Dental Realtor Services for Office Locations in Plano

Practice valuation increases when you choose locations with high visibility from major traffic arteries like Preston Road and Legacy Drive. These prime corridors support expanded hygiene programs through consistent patient flow and referral generation. Local demographic shift projections show continued affluent family growth through 2029, creating sustainable revenue streams for preventive and cosmetic services. Our dental real estate services in Plano connect you with spaces where location drives patient acquisition and long-term practice equity. Chat with a dental realtor to secure your space today.

Medical Practices

Professional Plano Medical Real Estate Agent for Doctors

Medical City Plano and Presbyterian proximity creates referral advantages with diagnostic center adjacency for coordinated care. Balanced exam-to-procedure room ratios support value-based contracts in West Plano and Legacy areas showing 15% annual population growth. Small medical offices in these corridors connect practices with affluent patients and specialist networks that generate consistent revenue. Reserve your medical space today.

Speciality Practices

Securing the Right Specialty Medical Office Space in Plano

Specialty practices need specific infrastructure such as ground-floor access for mobility patients, lead-lined walls for imaging, 200-amp panels for equipment. Presbyterian and Medical City Plano proximity builds physician referrals. Plano’s fitness-focused Legacy West and Shops at Willow Bend areas attract wellness-paying patients. We match your practice requirements with spaces that work. Get your specialty office space now.

Which Plano Areas Support the Most Medical Practice Growth?

Plano’s $108,649 median income and 22.6% Asian population drive strong specialty medical demand. Market gaps exist in dermatology and cardiology near Texas Health Presbyterian. Toyota and JCPenney headquarters provide healthcare benefits to 291,000 residents. Northeast sections show consistent growth many brokers miss. Our referral data pinpoints locations for maximum patient volume.
Average cost per sqft for medical office space in Texas.

Plano Office Lease Data & Trends

Plano medical office space ranges from $25-35 per square foot, reflecting its status as a premium Dallas suburb with top-tier healthcare facilities. Healthcare professionals generally secure 7-10 year lease commitments to justify specialized tenant improvements in this affluent North Texas community.

Plano Demographics & Growth

Plano's steady annual population growth reached 300k residents in 2025, making it Texas's ninth-largest city with the highest median income at $108,649. The region experiences significant primary care physician shortages, with many areas designated as Health Professional Shortage Areas.

Logistics & Zoning in Plano

Plano accommodates medical practices through updated zoning ordinances allowing healthcare facilities in commercial and mixed-use districts, with excellent patient connectivity via US-75, Dallas North Tollway, and major arterials throughout the Dallas-Fort Worth metroplex.

Single Site Study

$399/site

Know exactly where ideal patients are. Our single-site analysis maps demographics, income, and market saturation rates, revealing underserved pockets where demand exceeds supply. Determine if your desired location generates the patient volume and revenue you need. Order your market intelligence report now.

Custom Area Study

$300/100K people

Discover highest-opportunity locations across any market. Our custom study divides regions into 3-mile catchment zones, scoring each for practice viability. Perfect for multi-site expansion or location selection. Compare dozens of potential sites simultaneously. Strategic intelligence priced per 100,000 population.

Get a Rental Expense Estimate

Estimate your yearly rent, startup loan amount, buildout costs, and more.

Real Estate Expense Estimator

Practice Real Estate Expense and Timeline Estimate Generator

With 4 quick questions and about one minute of your time, we can send you an estimate of what your monthly rent, property expenses, and build-out loan payment for your practice will be.

We also include a purchasing budget equivalent to those rental rates if you are considering purchasing your real estate. Finally, you'll get a general timeline on when you might expect to be open.

Your packet will be emailed to you instantly when you hit submit.


Our Proven Commercial Office Leasing Process

Step 1

Practice Needs Analysis

Step 2

Research/ Site Selection

Step 3

Property Tours & Evaluation

Step 4

Lease Negotiation & Terms

Step 5

Opening Coordination

Common Questions About Plano Healthcare Real Estate

What Plano areas will work best for my practice?

Plano’s best areas depend on matching your specialty with referral networks and payment models. West Plano attracts cash-pay cosmetic practices near affluent neighborhoods, while Central Plano suits insurance-based specialties near medical complexes, and East Plano works for family practices targeting growing residential areas.

Insurance-dependent practices need proximity to hospital referral sources and established medical districts, while cash practices benefit from affluent demographics regardless of medical infrastructure. Measure patient sustainability through population growth and income stability metrics.

What’s the per-square-foot cost for medical office space in Plano, TX?

Medical office space in Plano typically ranges from $28-$35 per square foot annually, with ground floor spaces running $32-$35 and upper floors $28-$32. Operating expenses add another $8-$12 per square foot annually.

A 4,000 square foot multi-physician practice might total $13,000-$15,000 monthly, while a 1,500 square foot dermatology office runs $5,000-$6,500 monthly. Break-even typically requires 15-20 patients daily. Our commercial real estate brokers can provide current market-specific pricing.

Can working with a broker really help with spaces I found myself?

Working with a broker makes a huge difference even when you’ve already found the space you want. We negotiate personal guarantee limitations so you’re not personally liable for the full lease amount, protect against hidden liabilities like environmental issues, and create flexible lease terms that let you adjust as your practice grows. You’re smart to do your own research first.

We also build in exit strategy provisions if you need to leave early and identify hidden costs that landlords often bury in lease language. Most importantly, we check that parking ratios work for patient volume because inadequate parking kills medical practices. Commercial real estate agents prevent these costly mistakes, and our services cost you nothing since landlords pay our fees.

Proudly Serving Medical Organizations Throughout Texas:

Find Your Medical Office Space Now

Start your search with our medical property real estate specialists. We’ll negotiate better terms, protect your interests, and get landlords to pay our fees while you focus on patient care.
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List Your Property With Practice Real Estate Group

We fill medical spaces faster with qualified healthcare tenants, maximize your rental income through targeted marketing, and handle tenant screening while you collect rent checks.

List Your Property

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Order Your Custom Medical Site Analysis Report

Get demographic data, competitor mapping, patient flow patterns, and revenue projections for your specific location.
Area Study

By submitting this form, you consent to allowing Practice Real Estate Group to store and process the personal information to provide you with the requested content as well as other communications and updates. Check out our Privacy Policy to learn how we protect and manage your data.