Lease Medical & Dental Office Space in Houston, TX

Houston Healthcare Listings with Square Footage, Pricing, and Lease Terms

Your practice needs a location where patient volume meets projections from opening day. We match healthcare providers with spaces based on demographic data and competition density, then negotiate lease terms that protect your interests. Browse Houston medical office spaces selected for your specialty.

Available Medical Space Listings

Find Your Perfect Medical Office Space in Houston, TX

Search 28+ available medical office spaces in Houston, Texas. You’ll find properties from 1,200 to 15,000+ square feet that work for dentists, specialists, and multi-physician clinics.
TitleLocationAddressSale or LeaseListing Statushf:tax:locationhf:tax:sale_or_leasehf:tax:listing_status
Bandera, TX Commercial Space
Bandera, TX Commercial SpaceSan Antonio4003 TX-173, Bandera, TX 78003Sale or LeaseSpaces Availablesan-antonio texassale-or-leasespaces-available
Medical office round rock tx at 16010 Park Valley Dr Suite 300
Move-In Ready Medical Office Round Rock TX | 2,320 SFAustin16010 Park Valley Drive Suite 300, Round Rock, TXLeaseSpaces Availableaustin texasleasespaces-available
Medical office Austin TX exterior showing modern professional building on Manor Road with parking
Medical Office For Lease in Austin | Turnkey Space with Operating RoomAustin3607 Manor Rd, Ste. 101, Austin, Texas 78758LeaseSpaces Availableaustin texasleasespaces-available
dental office dripping springs tx
Dental Office For Sale or Lease in Dripping Springs TX | 4,100 SF Turnkey SpaceAustin13341 US HIGHWAY 290 Building 1-106 Austin, TX 78737Sale or LeaseSpaces Availableaustin texassale-or-leasespaces-available
Dental office Beaumont TX street view of freestanding building in established plaza
Dental Office Beaumont TX | Fully Equipped $725,000 Turnkey PracticeTexas3590 Blackmon Lane Beaumont, TX 77706SaleSpaces Availabletexassalespaces-available
Maine Medical Real Estate For Sale/Lease
Maine Medical Real Estate For Sale/LeaseMaineMaine, MESale or LeaseSpaces Availablemainesale-or-leasespaces-available
Medical office Plano TX clinical treatment room with specialized medical chair and professional healthcare equipment
Medical Office For Sale in Plano TX | 938 SF Turnkey Medical FacilityDallas Fort Worth3465 National Drive, Plano, TX 75025SaleSpaces Availabledallas-fort-worth texassalespaces-available
Medical office Prosper TX at Whispering Gables Office Park featuring modern 2020 construction
Medical Office For Lease in Prosper TX | 2,894 SF Modern SpaceDallas Fort Worth, Prosper123 Whispering Gables Drive, Suite 20 Prosper, TX 75078LeaseSpaces Availabledallas-fort-worth prosper texasleasespaces-available
Medical Office Space Leander TX - Pointe 183 Development
Medical Office Space Leander TX – Pointe 183 DevelopmentAustin10861 183A Leander, TX 78641LeaseSpaces Availableaustin texasleasespaces-available
Retail space for lease Plano TX at Plano Business Park showing modern commercial building exterior with glass windows and professional landscaping
Retail Space for Lease Plano TX | Prime 18,500 SF Development OpportunityDallas Fort Worth, Plano4065 E Plano Pkwy, Plano, TX 75074LeaseSpaces Availabledallas-fort-worth plano texasleasespaces-available
Medical space for sublease Hurst TX exterior view at The Shops at North East Mall showing signage and retail medical location
Medical Office for Lease Hurst TX | 2,100 SF Turnkey FacilityDallas Fort Worth, Hurst804 NE Mall Blvd, Hurst, TX 76053LeaseSpaces Availabledallas-fort-worth hurst texasleasespaces-available
Dental Office for Lease Houston TX | First-Generation Suite
Dental Office for Lease Houston TX | First-Generation SuiteHouston, Texas10101 Bissonnet Street, Houston, TX 77036LeaseSpaces Availablehouston texasleasespaces-available
Medical Office Space Sienna TX | New 16,000 SF by MD Anderson
Medical Office Space Sienna TX | New 16,000 SF by MD AndersonHouston, SiennaState Hwy 6 and Sienna Ranch Rd, Missouri City, TXLeaseSpaces Availablehouston sienna texasleasespaces-available
Medical office for lease Austin TX featuring 2,377 SF second-generation space in South Austin
Medical Office for Lease Austin TX | Prime 2,377 SF South LocationAustin, Texas6211 W William Cannon Drive, Austin, TX 78749LeaseSpaces Availableaustin texasleasespaces-available
Medical Office for Sale Coppell TX | 2,281 SF Move-In Ready Condo
Medical Office for Sale Coppell TX | 2,281 SF Move-In Ready CondoCoppell, Dallas Fort Worth149 TX, 121 Suite 105, Coppell, TX 75019SaleSpaces Availablecoppell dallas-fort-worth texassalespaces-available
Medical office Fort Worth featuring 1,569 SF turn-key space on 7th Street
Medical Office For Lease Fort Worth TX | Prime 7th Street LocationDallas Fort Worth2831 W 7th Street, Fort Worth, TX 76107LeaseSpaces Availabledallas-fort-worth texasleasespaces-available
Second Generation Dental Space in Cleburne, TX
Second Generation Dental Space in Cleburne, TXCleburne, Dallas Fort WorthCleburne, TXSale or LeaseSpaces Availablecleburne dallas-fort-worth texassale-or-leasespaces-available
Commercial Land For Sale in Cleburne TX | Prime 2.81 AC Development Opportunity
Commercial Land For Sale in Cleburne TX | Prime 2.81 AC Development OpportunityCleburne, Dallas Fort Worth1808 West Henderson Street, Cleburne, TX 76033SaleVacant sitecleburne dallas-fort-worth texassalevacant-site
Medical office South Austin at intersection of Menchaca Rd and FM 1626 with high visibility
Medical Office South Austin | Prime 4,469 SF Investment OpportunityAustin, Texas12117 Menchaca Road, Austin, TX 78748SaleSpaces Availableaustin texassalespaces-available
Medical Office For Sublease Westlake | Turnkey 1,987 SF Space
Medical Office For Sublease Westlake | Turnkey 1,987 SF SpaceAustin, TexasMedical-Office-For-Sublease-Westlake-1987SF-Turnkey-Space-Davenport-Village.pdfLeaseSpaces Availableaustin texasleasespaces-available
Medical Office for Lease in Southlake TX | Modern 2,635 SF Healthcare Space
Medical Office for Lease in Southlake TX | Modern 2,635 SF Healthcare SpaceDallas Fort Worth, Southlake2915 E Southlake Blvd, Southlake, TX 76092LeaseSpaces Availabledallas-fort-worth southlake texasleasespaces-available
Class A South Austin Medical Office | New Construction Suites with Surgery Center
Class A South Austin Medical Office | New Construction Suites with Surgery CenterAustin, Texas9010 Brodie Lane, Austin, TX 78748LeaseSpaces Availableaustin texasleasespaces-available
Medical Space For Sale or Lease in Georgetown TX | 5,465 SF New Construction
Medical Space For Sale or Lease in Georgetown TX | 5,465 SF New ConstructionAustin, Georgetown2021 Kaufman Loop, Unit 110, Georgetown, TX 78628Sale or LeaseSpaces Availableaustin georgetown-austin texassale-or-leasespaces-available
Retail Space For Sale in South Austin TX | Versatile 1,256 SF Storefront
Retail Space For Sale in South Austin TX | Versatile 1,256 SF StorefrontAustin, Texas4361 S Congress Ave Suite 106 Austin, TX 78745SaleSpaces Availableaustin texassalespaces-available
Dental Office For Sale in San Antonio TX | Established Somerset Practice
Dental Office For Sale in San Antonio TX | Established Somerset PracticeSan Antonio, Texas1445 Somerset Road # 4, San Antonio, TX 78211SaleSpaces Availablesan-antonio texassalespaces-available
Retail Space For Lease in East Austin TX | Prime 4,599 SF Near Mueller
Retail Space For Lease in East Austin TX | Prime 4,599 SF Near MuellerAustin, Texas4100 E 51st Street, Austin, TX 78723LeaseSpaces Availableaustin texasleasespaces-available
Medical Condo For Sale or Lease in Austin TX | Professional 4,889 SF Suite
Medical Condo For Sale or Lease in Austin TX | Professional 4,889 SF SuiteAustin, Texas3807 Spicewood Springs Road, Austin, TX 78759Sale or LeaseSpaces Availableaustin texassale-or-leasespaces-available
Medical Office For Sale or Lease in Round Rock TX | Prime 2,118 SF Condo
Medical Office For Sale or Lease in Round Rock TX | Prime 2,118 SF CondoAustin, Round Rock4010 Sandy Brook Drive, Round Rock, TX 78665Sale or LeaseSpaces Availableaustin round-rock texassale-or-leasespaces-available
Medical office Dripping Springs TX featuring modern Sawyer Ranch Medical Towers building with stone facade and professional landscaping
Medical Office For Lease in Dripping Springs TX | Sawyer Ranch Medical TowersAustin, Dripping Springs13830 Sawyer Ranch Road, Dripping Springs, TX 78620LeaseSpaces Availableaustin dripping-springs texasleasespaces-available
Medical office North Austin exterior view of Plaza North medical building with professional landscaping and modern architecture near St. David's Medical Center.
Medical Office Space For Lease in North Austin | Turnkey 1,905 SF Medical CondoTexas12319 N Mopac Expy, Austin, TX 78758LeaseSpaces Availabletexasleasespaces-available
Medical Condo For Lease in Cedar Park | 1,892 SF Class A Office Space
Medical Condo For Lease in Cedar Park | 1,892 SF Class A Office SpaceAustin, Cedar Park1513 E New Hope Drive, Bldg B, Austin, TX 78641LeaseFully Leasedaustin cedar-park texasleasefully-leased
Commercial land Garland TX aerial view showing 1.258 AC site adjacent to Winco Foods near I-635
Commercial Land For Sale in Garland TX | Prime 1.258 AC Development OpportunityDallas Fort Worth, Garland, TexasSEQ I-635 & Centerville Road, Garland, Texas 75041SaleVacant sitedallas-fort-worth garland texassalevacant-site
New Construction For Lease in Bee Cave TX | Professional Building on Highway 71
New Construction For Lease in Bee Cave TX | Professional Building on Highway 71Austin, TexasState Highway 71 & Del Dios Way, Austin, TX 78738LeaseSpaces Availableaustin texasleasespaces-available
Building
Office Building For Sale in Humble TX | Prime 21,705 SF Investment OpportunityHouston, Texas19411 McKay Boulevard, Humble, TX 77338SaleSpaces Availablehouston texassalespaces-available
Exceptional second-generation dental office available for lease.
Dental Office For Lease in Humble TX | Second Generation Space with 4 OperatoriesHouston19411 McKay Drive Humble, TX 77338LeaseSpaces Availablehouston texasleasespaces-available
Office Space For Lease in Boerne TX | Prime Location with Excellent Accessibility
Office Space For Lease in Boerne TX | Prime Location with Excellent AccessibilityBoerne, San Antonio, Texas415 South School Street, Boerne, TX 78006LeaseSpaces Availableboerne san-antonio texasleasespaces-available
Aransas Pass Healthcare Space
Medical Office For Sale in Aransas Pass TX | 60,445 SF Healthcare Anchor OpportunityAransas Pass, Texas1711 W Wheeler Ave, Aransas Pass TX, 78336Sale or LeaseSpaces Availablearansas-pass texas corpussale-or-leasespaces-available
Medical Office For Sale or Lease in Georgetown TX | 17,000 SF Class A DB Woods Development
Medical Office For Sale or Lease in Georgetown TX | 17,000 SF Class A DB Woods DevelopmentAustin, GeorgetownNEQ Highway 29 & DB WoodsSale or LeaseSpaces Availableaustin georgetown-austin texassale-or-leasespaces-available
Located in the growing Hutto Community right down the street from the fire station.  This is a great location for a medical office due to an optometrist and dentist being located at the project.  General office use is also allowed and it is near multiple eateries and retail shops.
Medical Office For Lease in Hutto TX | 2,000 SF Professional Space at 401 Exchange BlvdAustin, Hutto401 Exchange Blvd, Hutto, TX 78634LeaseSpaces Availableaustin hutto texasleasespaces-available
Healthcare Expertise General Commercial Real Estate Brokers Can't Match

Houston's Leading Healthcare Property Specialists

Find available medical office space in Houston, TX.

Houston Medical Real Estate Brokers

General commercial brokers treat medical offices like standard office space. We analyze Houston's healthcare market using patient demographics, competition density, and specialty-specific requirements. We examine population health data, insurance coverage rates, and referral network proximity to identify locations where your practice can build patient volume.

Market Reports for Houston Healthcare Office Space for Lease

Memorial has 42% of residents over 65, which creates strong patient volume for cardiology and geriatric practices. Sugar Land has 78,000 households earning $150K or more, which supports demand for cosmetic and elective procedures. We analyze provider density, referral patterns, and population growth by neighborhood. Find locations where competition is limited and patient demand matches your specialty.

Houston Medical Office Selection That Matches Your Specialty

We find Houston offices that work for your specialty, covering medical gas, specialized plumbing, and ADA layouts so you can operate from day one. Pediatric practices typically need 3,500 square feet in Pearland's family neighborhoods. Cardiology groups require 5,000+ square feet near Memorial hospitals with reinforced floors for imaging equipment. We verify infrastructure before you tour.

Find, Negotiate, and Secure Your Ideal Space, With Representation That Puts You First

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Houston Medical Real Estate Services for Every Practice

The wrong location breaks practices. The right location builds them. Houston physicians and dentists get the right one with us. Our Texas healthcare real estate agents understand why orthopedic surgeons need different infrastructure than dermatologists, saving you months of expensive delays.
5-star Google Rated commercial real estate brokerage in Houston, TX.

Medical Office Spaces for Rent That Fit Your Practice

Find healthcare office space with lease terms that support practice growth and future transitions. We identify Houston locations with strong patient demographics while securing agreements that protect your interests and get you competitive rates.
Our healthcare real estate agents in Houston, TX are experts in helping clients find the best possible office space.

Location Analysis That Protects Your Investment

Before signing any Houston medical space lease, you need market data that protects your investment. We analyze patient demand for your specialty, identify underserved zip codes, and pinpoint locations where practices reach profitability faster. Our Houston market data positions your practice for growth from opening day.

List Your Medical Office Space for Rent

Skip the endless showings and unqualified leads. We market your space with professional photography and virtual tours directly to our physician network. Our team structures long-term medical leases averaging 5+ years and handles every tenant interaction. You collect rent while we manage the relationship. Secure healthcare tenants for your Houston property today.

General Brokers Don't Understand Healthcare. We Do.

Practice Real Estate Group vs other broker types
Practice Real Estate Group is the best healthcare real estate firm. Practice Real Estate Group General Commercial Brokers National CRE Firms
Market Expertise 100% healthcare focus with specialty specific demographic analysis. Treats medical like any standard office space. Corporate red tape with minimal healthcare specialization.
Medical Space Knowledge Expert in medical office build outs ADA medical gas and HVAC requirements. Basic knowledge with gaps in practice needs. Refers to outside specialists, adding time and money.
Patient Demographics Healthcare specific data insurance coverage and competition mapping. Generic data without patient utilization insight. Standard reports.
Lease Negotiations Medical focused lease terms expansion rights and equipment clauses. Standard terms missing key healthcare protections. Corporate terms with less focus on individual practices.
Professional Network Vetted healthcare network contractors, lenders, and vendors. General contractors, limited healthcare ties. Corporate vendors that exceed practice budgets.
Practice Understanding Deep specialty knowledge workflow and patient accessibility needs. One size fits all approach, limited expertise. Focus on square footage vs practice function.
Client Focus Dedicated attention from expert five star medical real estate agents. Attention split across property types. Priority on the largest corporate deals.

Dental Practices

Find Dental Office Space for Lease in Houston

Pediatric dental practices in Houston suburbs grow 30% faster than general dentistry. Three-mile competition analysis shows Cypress and Pearland need more family dentists, with less than 1 dentist per 1,000 residents in both areas. Our dental real estate services position you to build $2M+ practice value within five years. Houston adds 30,000+ new residents annually, creating constant patient demand. Start your search today.

Medical Practices

Find the Perfect Medical Office Space for Lease in Houston

Building your patient panel to 2,000+ patients starts with location. Houston’s 77024 and 77401 zip codes have 85% commercial insurance coverage, meaning better reimbursement rates. Medical office space with HIPAA-compliant storage positions you for Memorial Hermann ACO contracts. Proximity to Texas Medical Center brings specialist referrals. We’ll show you where practices grow with specialty-specific data.

Speciality Practices

Specialty Healthcare Office Space​s in Houston

Mental health practices succeed near corporate hubs. PT clinics need ground-floor access in neighborhoods with aging populations. Cash-pay wellness centers thrive in affluent zip codes. Veterans seek imaging near VA facilities. Houston’s medical corridor offers sound insulation, inspection-ready layouts, and locations where your target patients already go. Get a location where referrals happen automatically.

Find The Best Location in Houston for Your Medical Practice

Houston practices generate 23% higher revenues near referral sources. Our location mapping tracks 1,200+ physician groups, 312 senior facilities, and hospital systems to identify referral corridors. We map specialist-to-primary-care referral patterns so you can see where patient flow concentrates. This data helps you capitalize on Houston’s $3.2 billion medical corridor expansions and Grand Parkway connections while avoiding saturated areas.
Average cost per sqft for medical office space in Texas.

Houston Medical Office Lease Data and Trends

Medical office space in Houston leases for $22-26 per square foot annually on a triple-net basis. Most practices sign 3-5 year terms, with established specialists often committing to 7-10 years for better tenant improvement allowances.

Houston Demographics & Growth

Houston's population grew 9.8% since 2020, adding 230,000 potential patients. The city has 3.35 healthcare workers per 100 residents, ranking among America's most underserved major metros. That's opportunity.

Logistics & Zoning in Houston

Houston's no-zoning ordinances allow medical practices in most commercial areas, giving you more location options than other major metros. METRO's Red Line provides direct rail access to Texas Medical Center with trains running every 6-12 minutes during peak hours.

Single Site Study

$399/site

Know exactly where ideal patients are. Our single-site analysis maps demographics, income, and market saturation rates, revealing underserved pockets where demand exceeds supply. Determine if your desired location generates the patient volume and revenue you need. Order your market intelligence report now.

Custom Area Study

$300/100K people

Discover highest-opportunity locations across any market. Our custom study divides regions into 3-mile catchment zones, scoring each for practice viability. Perfect for multi-site expansion or location selection. Compare dozens of potential sites simultaneously. Strategic intelligence priced per 100,000 population.

Get a Rental Expense Estimate

Estimate your yearly rent, startup loan amount, buildout costs, and more.

Real Estate Expense Estimator

Practice Real Estate Expense and Timeline Estimate Generator

With 4 quick questions and about one minute of your time, we can send you an estimate of what your monthly rent, property expenses, and build-out loan payment for your practice will be.

We also include a purchasing budget equivalent to those rental rates if you are considering purchasing your real estate. Finally, you'll get a general timeline on when you might expect to be open.

Your packet will be emailed to you instantly when you hit submit.


Our Proven Commercial Office Leasing Process

Step 1

Practice Needs Analysis

Step 2

Research/ Site Selection

Step 3

Property Tours & Evaluation

Step 4

Lease Negotiation & Terms

Step 5

Opening Coordination

Frequently Asked Questions About Healthcare Real Estate In Houston

How do I know if Houston is the right location for my practice?

Houston fits your practice when patient demographics match your specialty. Memorial’s executive population works for cardiology groups. Bellaire’s multicultural communities support family medicine. Montrose’s health-conscious residents are a strong fit for wellness centers. Each neighborhood serves different patient needs and insurance mixes.

Spanish-speaking population density should align with your staff’s language capabilities, and insurance mix data should match your billing model. The competitive advantage comes from identifying opportunities others miss. Request our Houston market analysis showing physician-to-population ratios by zip code.

What are the typical costs per square foot for medical office space in Houston?

Houston medical office space typically costs $24-35 per square foot annually in suburban areas, though you’ll pay $30-42 per square foot near medical centers. Parking adds $20-100 monthly per space depending on location, which adds up for busy practices.

Physical therapy clinics at 2,000-3,000 square feet should budget $4,000-8,750 monthly. Multi-physician groups at 4,000-5,000 square feet should budget $8,000-14,600 monthly. Exit clauses protect your investment if plans change, and we can help you negotiate them. Talk to our Houston healthcare team for a cost estimate specific to your specialty.

Do I need a real estate agent if I've already found spaces I'm interested in?

Yes. Professional representation protects your interests even after you’ve found spaces. You’ve done the initial work, and now we negotiate personal guarantee caps, early termination options, and exclusive-use provisions that prevent competitors from moving nearby. These details save tens of thousands over a typical lease term.

Medical practices face challenges that standard leases overlook, like medical waste handling provisions, liability limitations, and exit strategy clauses. Our healthcare-specific lease expertise prevents expensive surprises. And landlords cover our fees, so you get professional negotiation at no additional cost. Why leave money on the table?

Proudly Serving Medical Organizations Throughout Texas:

Find Your Medical Office Space Now

Start your search with our medical property real estate specialists. We’ll negotiate better terms, protect your interests, and get landlords to pay our fees while you focus on patient care.
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List Your Property With Practice Real Estate Group

We fill medical spaces faster with qualified healthcare tenants, maximize your rental income through targeted marketing, and handle tenant screening while you collect rent checks.

List Your Property

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Order Your Custom Medical Site Analysis Report

Get demographic data, competitor mapping, patient flow patterns, and revenue projections for your specific location.
Area Study

By submitting this form, you consent to allowing Practice Real Estate Group to store and process the personal information to provide you with the requested content as well as other communications and updates. Check out our Privacy Policy to learn how we protect and manage your data.