Houston Medical Real Estate for Lease

Looking for premium medical office space Sienna TX? This exceptional 16,000 SF opportunity is strategically located at State Hwy 6 and Sienna Ranch Rd in the thriving Sienna Plantation community. Positioned in the Sienna Plantation Medical Center with MD Anderson as the first-floor tenant, this property offers healthcare providers exceptional visibility and prestigious association. Construction is currently underway with scheduled core and shell delivery in Q4-2025.

Prime Sienna Medical Location

• Prominent State Hwy 6 and Sienna Ranch Rd intersection with high visibility
• First-floor anchor tenant: MD Anderson Cancer Center
• Surrounded by affluent residential communities in Sienna Plantation
• Near multiple schools including Elkins High School and Sonal Bhuchar Elementary
• Adjacent to established retail including Lifetime Fitness, HEB, and numerous restaurants
• Easy access from multiple residential communities within Sienna

Premium Medical Office Features

• 16,000 SF full-floor opportunity on the second floor in shell condition
• Part of a modern 32,000 SF medical building
• New construction with delivery scheduled for Q4-2025
• Flexible build-out options to meet healthcare providers’ specific needs
• Generous $45/SF tenant improvement allowance
• Ample surface parking at 5 spaces per 1,000 SF

Exceptional Demographics

• 196,209 population within 5-mile radius (2024)
• $151,131 average household income
• $361,975 median home value
• $643.9M consumer spend on healthcare within 5 miles
• Strong insurance mix with 71.4% private insurance coverage
• Growing residential population in surrounding master-planned communities

This medical office space Sienna TX opportunity represents one of the area’s premier healthcare locations. The building’s association with MD Anderson provides instant credibility and visibility in the medical community. Sienna continues to be one of the fastest-growing communities in the Houston metro area.

For healthcare providers seeking office space near Texas Medical Center, this Sienna location offers an excellent satellite option in one of Fort Bend County‘s most affluent areas.

Leasing Information

• Rent: Call for Pricing
• NNN: $10.44 SF
• $45 Tenant improvement allowance
• Full floor availability for single tenant or multi-tenant options
• Customize your medical space with flexible build-out options

Healthcare providers seeking medical office space Sienna TX will appreciate the strategic location and growth potential of this property. With its prominent visibility, prestigious co-tenancy, and strong demographic support, this medical office space offers an exceptional opportunity for healthcare practices.

For more information about this medical office space for lease in Sienna, TX, contact Peter Hays at 713/409.9686 or explore more medical office listings from Practice Real Estate Group.